Jahrestagung GAMM 1956

Optimization of GAMM Francis Turbine Runner

Nowadays, the challenge in hydraulic turbine design is the multi-objective design of turbine runner to reach higher efficiency. The hydraulic performance of a turbine is strictly depends on runner blades shape. The present paper focuses on the application of the multi-objective optimization algorithm to the design of a small Francis turbine runner. The optimization exercise focuses on the effic...

/ GAMM Workshop on Coping with Uncertainty 13

Dominique Muller (1956–2015)

On April 29, 2015, the neuroscience community lost an accomplished and beloved scientist when Dominique Muller died in an accident in the French Alps south of Grenoble. He passed away doing his favorite pastime: plane gliding. Dominique had a fiery curiosity that is at the heart of good science. He lived his passion for research in the laboratory, combining experimental creativity, warm mentors...

Dmd052134 1949..1956

Prediction of clinical efficacy, toxicity, and drug-drug interactions may be improved by accounting for the intracellular unbound drug concentration (Cunbound) in vitro and in vivo. Furthermore, subcellular drug distribution may aid in predicting efficacy, toxicity, and risk assessment. The present study was designed to quantify the intracellular Cunbound and subcellular localization of drugs i...

C3em00214d 1949..1956

Institute of Environmental Systems Barbarastraße 12, D-49076 Osnabrueck, Ge 2 38 64 3668 Department of Biology/Chemistry, Divisio Barbarastraße 13, D-49076 Osnabrueck, Ge Environmental Mineralogy, Institute for Ap Darmstadt, Schnittspahnstr. 9, D-64287 Da † Electronic supplementary informa 10.1039/c3em00214d ‡ Present address: Water, Environment an Recherches Géologiques et Minières (BRG 36009,...